Diclofenac Sodium Tablets 100 mg

What is Diclofenac Sodium Tablets 100 mg?

Diclofenac Sodium Tablets 100 mg contain diclofenac sodium, an NSAID used for the short-term management of pain and inflammation associated with various musculoskeletal and inflammatory conditions. The product is available in tablet form and can be sourced for international pharmaceutical supply according to applicable market requirements.

Uses / Indications

Diclofenac Sodium Tablets 100 mg may be used for the management of pain and inflammation associated with conditions such as:

• Musculoskeletal pain and inflammatory disorders
• Osteoarthritis and rheumatoid arthritis
• Acute painful inflammatory conditions
• Soft-tissue inflammation and pain
• Other conditions where an NSAID is clinically indicated

Use should be based on the approved product information and advice of a qualified healthcare professional.

Benefits

• Helps relieve pain associated with inflammatory conditions.
• Helps reduce inflammation and associated discomfort.
• Provides an oral tablet dosage form for convenient administration.
• Suitable for pharmaceutical sourcing and supply for applicable markets.
• Available in Alu-PVC and Alu-Alu blister packaging options.

Side Effects

Common Side Effects

Possible side effects may include:

• Nausea or vomiting
• Indigestion or stomach discomfort
• Abdominal pain
• Diarrhea or constipation
• Headache or dizziness

Less Common or Serious Side Effects

NSAIDs such as diclofenac can, in some patients, cause serious gastrointestinal, cardiovascular, renal, hepatic, or allergic reactions. Seek prompt medical attention for signs such as gastrointestinal bleeding, severe allergic reaction, chest pain, difficulty breathing, significant swelling, or unusual changes in urine.

How Does It Work?

Diclofenac sodium works primarily by inhibiting cyclooxygenase (COX) enzymes involved in the production of prostaglandins. Prostaglandins contribute to pain, inflammation, and fever. By reducing prostaglandin production, diclofenac helps reduce pain and inflammatory symptoms.

Dosage Guidelines

• The appropriate dose and duration depend on the patient’s condition, age, medical history, and response to treatment.
• Diclofenac Sodium Tablets 100 mg should be taken only according to approved prescribing information or the direction of a qualified healthcare professional.
• Tablets should be swallowed with water and should not be crushed or chewed unless specifically permitted for the particular formulation.
• The lowest effective dose for the shortest appropriate duration is generally preferred for NSAID therapy.
• Do not exceed the recommended dose.

When Not to Use

Diclofenac should generally be avoided or used only under appropriate medical supervision in individuals with:

• Known hypersensitivity to diclofenac or other NSAIDs
• Previous NSAID-associated allergic reactions such as asthma, urticaria, or acute rhinitis
• Active gastrointestinal ulceration or bleeding
• Certain significant cardiovascular, renal, or hepatic conditions where NSAID treatment is inappropriate
• The peri-operative setting of coronary artery bypass graft surgery

The complete approved prescribing information should be reviewed before use.

Drug / Product Interactions

Diclofenac may interact with medicines such as:

• Other NSAIDs or salicylates
• Anticoagulants and antiplatelet medicines
• Corticosteroids
• Certain antihypertensive medicines
• Diuretics
• Lithium
• Methotrexate
• Ciclosporin or tacrolimus
• Certain medicines affecting kidney function

Patients should inform their healthcare professional about all prescription medicines, non-prescription medicines, and supplements they use.

Safety Advice

• Use only as directed by a qualified healthcare professional.
• Avoid combining with other NSAIDs unless specifically advised.
• Patients with a history of gastrointestinal ulceration, cardiovascular disease, kidney disease, liver disease, or hypertension should seek medical advice before use.
• Report unusual stomach pain, black stools, vomiting blood, breathing difficulty, severe rash, or swelling promptly.
• Use during pregnancy, particularly later pregnancy, only according to appropriate medical advice.
• Breastfeeding and pediatric use should follow approved prescribing information and professional guidance.
• Patients who experience dizziness or other effects that impair alertness should exercise caution when driving or operating machinery.

General Instructions

• Take the medicine exactly as prescribed.
• Swallow the tablet with sufficient water.
• Do not take more than the recommended dose.
• Avoid taking additional diclofenac-containing products unless advised by a healthcare professional.
• Keep the product out of reach of children.
• Always follow the approved label and product leaflet for the relevant market.

Special Dietary / Lifestyle Tips

• Take the medicine with food or after food if advised or if stomach discomfort occurs.
• Avoid excessive alcohol consumption, as it may increase gastrointestinal risks associated with NSAID use.
• Maintain adequate fluid intake unless fluid restriction has been recommended for another medical condition.
• Follow appropriate physical activity and other condition-specific measures recommended by a healthcare professional.

Comparison with Other Treatments

Diclofenac is one of several NSAIDs used for pain and inflammation. Other options include ibuprofen, naproxen, and other approved anti-inflammatory medicines. The choice depends on the indication, patient-specific risk factors, concomitant medicines, treatment duration, and the approved product information. Different NSAIDs have different dosing schedules, contraindications, and safety considerations.

Precautions & Warnings

• Long-term or high-dose NSAID use may increase the risk of gastrointestinal, cardiovascular, renal, and hepatic adverse effects.
• Patients with previous gastrointestinal problems should discuss NSAID treatment with a healthcare professional.
• Patients with cardiovascular risk factors require appropriate clinical consideration before treatment.
• Kidney and liver function may require monitoring during prolonged treatment or in patients with relevant risk factors.
• Discontinue and seek medical attention if signs of a serious allergic reaction occur.
• Do not use beyond the recommended duration without medical supervision.

Can I Use It With Other Medicines?

Generally Compatible With

Diclofenac may be used alongside certain medicines when clinically appropriate and prescribed with consideration of the patient’s medical history and other treatments.

Use With Caution / Avoid

Particular caution is required when diclofenac is used with:

• Other NSAIDs
• Anticoagulants or antiplatelet agents
• Systemic corticosteroids
• Diuretics and antihypertensive medicines
• Lithium
• Methotrexate
• Ciclosporin or tacrolimus
• Other medicines that may affect kidney function

A healthcare professional should review the complete medication list before treatment.

Storage

• Store according to the storage conditions stated on the approved product packaging and leaflet.
• Keep the tablets in their original packaging until use.
• Protect the product from unsuitable environmental conditions.
• Keep out of reach and sight of children.
• Do not use after the expiry date.

Frequently Asked Questions

1. What is Diclofenac Sodium Tablets 100 mg used for?

It is an NSAID used for the management of pain and inflammation associated with various musculoskeletal and inflammatory conditions.

2. What is the active ingredient in this product?

Each tablet contains Diclofenac Sodium 100 mg.

3. Is Diclofenac Sodium Tablets 100 mg an antibiotic?

No. Diclofenac sodium is a non-steroidal anti-inflammatory drug (NSAID), not an antibiotic.

4. Can Diclofenac Sodium Tablets 100 mg be taken with other painkillers?

Some painkillers, particularly other NSAIDs, may interact with diclofenac or increase adverse-effect risks. A healthcare professional should confirm whether combination treatment is appropriate.

5. Can this medicine be used during pregnancy?

Diclofenac use during pregnancy requires medical guidance, with particular restrictions applying later in pregnancy. Consult a qualified healthcare professional before use.

6. Is this product available in different blister pack options?

Yes. The specified packaging includes 10×10 Alu-PVC Blister and 10×10 Alu-Alu Blister, with additional packaging configurations available as per requirement.

7. Does Kelar Pharmachem India manufacture this product?

Kelar Pharmachem India provides global pharmaceutical sourcing and export solutions. Manufacturing arrangements depend on the specific product and sourcing requirement.